In the treatment of periorbital melanoma, microscopically controlled surgery not only provides great assurance of eradicating the primary melanoma and managing possible satellites, but it also permits maximal sparing of adjacent normal tissues, a benefit of particular value around such important structures as the eyes. The fixed-tissue technique is employed when there is no involvement of the lid margins or bulbar conjunctiva, but if these structures are invaded the fresh-tissue technique with chemical cauterization of the incisional surface is used.
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Frederic E. Mohs (1985) studied this question.
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