Key result
Propafenone administration for chemical cardioversion of new onset atrial fibrillation unmasked Brugada syndrome in a 43-year-old man.
Case Report (n=1)
Emergency physicians should be aware that propafenone can unmask Brugada syndrome, presenting as right bundle branch block and ST segment elevation in right precordial leads.
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Alerts to propafenone-related Brugada unmasking in AF; single case leaves open need for prospective validation.
We report a case of a 43 year old man who was diagnosed with Brugada syndrome after propafenone administration for chemical cardioversion of new onset atrial fibrillation. Brugada syndrome has been described in the medical literature and is thought to be responsible for the majority of sudden cardiac deaths in patients without ischaemic heart disease. This syndrome has not yet been extensively discussed in the emergency medicine literature despite its importance. Emergency physicians should consider Brugada syndrome in patients who present to the emergency department with right bundle branch block and ST segment elevation in the right precordial leads, which is the classic electrocardiographic pattern of this syndrome.
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Ersin Aksay (2005) conducted a case report in Brugada syndrome and new onset atrial fibrillation (n=1). Propafenone was evaluated on Manifestation of Brugada syndrome (ST segment elevation). Propafenone administration for chemical cardioversion of new onset atrial fibrillation unmasked Brugada syndrome in a 43-year-old man.
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