EMBRYONIC AND FETAL HISTOMORPHOLOGICAL DIFFERENTIATION OF THE OCULAR STRUCTURES IN SPRAGUE DAWLEY RAT (Rattus norvegicus)

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Histological sections of the embryos and fetuses of the Sprague Dawley rats were usedto study the ocular developmental stages. Microscopic examination indicated that the primordialtissue related to the eye is found in the head fold region as an optic pit, then form the opticvesicle. The latter is invaginated upon itself to form the optic cup. The lens vesicle, which hadseparated from the ectoderm, was distinctly visible. Hence, lens capsule and fibers were evident.The front lens of the eye is derived from the superficial ectoderm and from the cornea.The optic vesicle is destined to form the retina. The mesenchymal cells found between themargins of the cup and the lens is involved in the formation of the vitreous body. In conclusion,the organogenesis of the ocular tissues in studied rats becomes evident when the optic cup andinvaginated lens placode were begun to be formed which can bemorphologically identified on the 12th embryonic day. The current information about theembryonic and fetal development of the rat’s eye gives more concepts for subsequentmorphological and physiological works or experiments.