Key result
Performing gastrointestinal endoscopy during the index hospitalization in patients with acute coronary syndrome and concomitant gastrointestinal bleeding was associated with lower mortality (OR 0.58).
Why the study?
Studies assessing the safety of gastrointestinal endoscopy in ACS patients with gastrointestinal bleeding are limited by small sample sizes and have predominantly focused only on upper gastrointestinal bleeding and esophago-gastroduod-enoscopy.
Does gastrointestinal endoscopy improve mortality and length of stay in patients hospitalized with acute coronary syndrome and concomitant gastrointestinal bleeding?
Observational (n=269,483)
Yes
Does gastrointestinal endoscopy improve mortality and length of stay in patients hospitalized with acute coronary syndrome and concomitant gastrointestinal bleeding?
Performing gastrointestinal endoscopy during the index hospitalization for patients with ACS and concomitant GIB is associated with lower mortality and shorter length of stay.
Answers are grounded in this paper and cite their sources.
May support index-hospitalization endoscopy in ACS with GIB; leaves open need for RCTs to confirm benefit.
BACKGROUND: Gastrointestinal bleeding (GIB) is a major concern in patients hospitalized with acute coronary syndrome (ACS) due to the common use of both antiplatelet medications and anticoagulants. Studies evaluating the safety of gastrointestinal endoscopy (GIE) in ACS patients with GIB are limited by their relatively small size, and the focus has generally been on upper GIB and esophago-gastroduod-enoscopy (EGD) only. AIM: To evaluate the safety profile and the hospitalization outcomes of undergoing GIE in patients with ACS and concomitant GIB using the national database for hospitalized patients in the United States. All analyses were performed using SAS 9.4 (Cary, NC, United States). CONCLUSION: Performing GIE during the index hospitalization of patients with ACS and GIB was correlated with a better mortality rate and a shorter LOS. Approximately two-thirds of patients with both ACS and GIB undergo GIE during the same hospitalization.
No takes yet. Share an insight, caveat, or question.
Elkafrawy et al. (2021) conducted an observational in Acute coronary syndrome and concomitant gastrointestinal bleeding (n=269,483). Gastrointestinal endoscopy vs. No gastrointestinal endoscopy was evaluated on In-hospital mortality (OR 0.58, 95% CI 0.53-0.63, p=<0.001). Performing gastrointestinal endoscopy during the index hospitalization in patients with acute coronary syndrome and concomitant gastrointestinal bleeding was associated with lower mortality (OR 0.58).
Synapse has enriched 10 related papers. Consider them for comparative context: