Targeting Dependency on the GPX4 Lipid Peroxide Repair Pathway for Cancer Therapy

ADVERTISEMENT RETURN TO ISSUEViewpointNEXTTargeting Dependency on the GPX4 Lipid Peroxide Repair Pathway for Cancer TherapyHengrui LiuHengrui LiuDepartment of Chemistry, Columbia University, New York, New York 10027, United StatesMore by Hengrui Liuhttp://orcid.org/0000-0002-5214-1572, Stuart L. Schreiber*Stuart L. SchreiberDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United StatesBroad Institute, Cambridge, Massachusetts 02142, United States*E-mail: [email protected]More by Stuart L. Schreiberhttp://orcid.org/0000-0003-1922-7558, and Brent R. Stockwell*Brent R. StockwellDepartment of Chemistry, Columbia University, New York, New York 10027, United StatesDepartment of Biological Sciences, Columbia University, 550 West 120th Street, MC 4846, New York, New York 10027, United States*E-mail: [email protected]More by Brent R. Stockwellhttp://orcid.org/0000-0002-3532-3868Cite this: Biochemistry 2018, 57, 14, 2059–2060Publication Date (Web):March 27, 2018Publication History Received13 March 2018Published online27 March 2018Published inissue 10 April 2018https://pubs.acs.org/doi/10.1021/acs.biochem.8b00307https://doi.org/10.1021/acs.biochem.8b00307editorialACS PublicationsCopyright © 2018 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views4974Altmetric-Citations63LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (381 KB) Get e-AlertscloseSUBJECTS:Cancer,Cancer therapy,Cells,Inhibitors,Lipids Get e-Alerts