Epstein-Barr viral (EBV) DNA has been regularly demonstrated in biopsy material from two different human tumors: Burkitt's lymphoma and nasopharyngeal carcinoma (zur Hausen et al. 1970, 1974b; Nonoyama and Pagano 1973; Wolf et al. 1973). Patients carrying either of these tumors reveal elevated antibody titers against EB viral capsid antigens (VCA) and in a high percentage also against EBV early antigens (EA) (Henle et al. 1970a,b).
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Wolf et al. (1974) studied this question.
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