Poly (styrene-divinylbenzene-acrylic acid) nanoparticles were synthesized through microemulsion polymerization using a three component oil-in-water microemulsion containing sodium dodecylsulphate. Stable and transparent poly (styrene–DVB-acrylic acid) nanolatexes were produced. The latexes were characterized for particle size and number of particles by dynamic light scattering and TEM. The isolated products were characterized by IR. The particles were further used for the loading of Acryflavin drug. Acryflavin was selected as a model drug to understand the behavior of in-vitro drug release pattern at different pH in nanoparticles.
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Sanghvi et al. (2005) studied this question.
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