The nucleophilic displacement reactions of 2- and 4- halogenonaphthalic-1,8, anhydrides and the N-imides, of 4,7- dichloroquinolines, the alkylation of lithio alkynes, the methylation of ethyl or methyl diacetylacetate and a variety of related reactions are greatly facilitated in N-methylpyrrolidinone as aprotic solvent.
No takes yet. Share an insight, caveat, or question.
Tyman et al. (1989) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: