Laparoscopic treatment of tubal pregnancies with 15-methyl-prostaglandin?2a

SummaryTubal pregnancies in 39 patients were treated by injection of 15-methyl-prostaglandin F2α into the tubal wall over the site of implantation. Postoperative stay varied from 12 to 60 hours. Patients were subsequently monitored as outpatients with serial estimations of β-human chorionic gonadotrophin (β-hCG) levels. Two women required a second injection with subsequent satisfactory resolution of the ectopic gestation and 3 women subsequently underwent salpingectomy. All women were offered hysterosalpingography 6 months after the procedure. Ten are still waiting to have the X-ray, 4 declined the offer, 11 women conceived with intra-uterine pregnancies before the hysterosalpingogram and 14 have had the X-ray performed. Of these 14, 10 have patency of the affected tube; in 3 of these there are peritubular adhesions. Three showed definite block of the affected tube and the other patient had findings suggestive of tubal spasm.