Key result
Higher C-reactive protein (OR 1.159; 95% CI 1.022-1.315) and lower serum potassium (OR 0.222; 95% CI 0.052-0.948) are independent risk factors for giant aneurysms in Kawasaki disease.
Why the study?
Are serum potassium and C-reactive protein levels independent risk factors for giant aneurysms in patients with Kawasaki disease?
Population
138 patients with Kawasaki disease, comprising 69 cases with giant aneurysms presenting within 9 days of…
Design
Case-control
Authors
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May refine Kawasaki disease risk stratification; hypothesis-generating and requires prospective validation.
Case-Control (n=138)
Yes
Are serum potassium and C-reactive protein levels independent risk factors for giant aneurysms in patients with Kawasaki disease?
Odds Ratio: 1.159 (95% CI 1.022–1.315)
Higher C-reactive protein and lower serum potassium levels on admission are independent risk factors for the development of giant coronary aneurysms in Kawasaki disease.
Koyanagi et al. (1998) conducted a case-control in Kawasaki disease (n=138). Serum potassium and C-reactive protein levels vs. Matched controls without coronary involvement was evaluated on Development of giant aneurysms (OR 1.159, 95% CI 1.022-1.315). Higher C-reactive protein (OR 1.159; 95% CI 1.022-1.315) and lower serum potassium (OR 0.222; 95% CI 0.052-0.948) are independent risk factors for giant aneurysms in Kawasaki disease.
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