Key result
E-cigarette use may induce comparable deleterious effects on weight and cardiometabolic parameters as conventional cigarette smoking, though human data remain limited.
Why the study?
Does e-cigarette use induce weight changes and increase cardiometabolic risk compared to regular cigarette smoke?
Does e-cigarette use induce weight changes and increase cardiometabolic risk compared to regular cigarette smoke?
This review highlights that e-cigarettes may carry similar cardiometabolic and weight-related risks as traditional cigarettes, challenging their perception as a healthier alternative.
May warrant caution against assuming e-cigarette cardiometabolic safety; leaves open definitive human risk comparisons.
The prevalence of non-cigarette tobacco use in electronic cigarettes, also called vaping, is rapidly increasing, especially in adolescents and young adults, due to attractive marketing techniques promoting them as healthier alternatives to conventional tobacco cigarettes. Although smoking is associated with weight loss, it increases insulin resistance and attributes to other features of the metabolic syndrome, increasing the cardiometabolic risk profile. Whether vaping has the same deleterious effects on metabolic parameters as regular cigarette smoke has not yet been studied thoroughly in humans. However, animal model experiments attribute comparable effects of e-cigarette smoking, even without nicotine exposure, on weight and metabolic parameters as compared to smoking cigarettes. In this review paper, we want to give an overview of published data on the effects on weight and cardiometabolic parameters of e-cigarette use and formulate some mechanistic hypotheses.
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Verhaegen et al. (2017) conducted a review in Cardiometabolic risk. E-cigarette use vs. Conventional cigarette smoking was evaluated on Weight and cardiometabolic parameters. E-cigarette use may induce comparable deleterious effects on weight and cardiometabolic parameters as conventional cigarette smoking, though human data remain limited.
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