Appearance of Miliary Tuberculosis Following Therapy With Acth and Cortisone in a Case of Acute Disseminated Lupus Erythematosus

Case Reports1 April 1953APPEARANCE OF MILIARY TUBERCULOSIS FOLLOWING THERAPY WITH ACTH AND CORTISONE IN A CASE OF ACUTE DISSEMINATED LUPUS ERYTHEMATOSUSALEX G. DAVIDSON, M.D., F.A.C.P., LEONARD FOX, M.D., JAY J. GOLD, M.D.ALEX G. DAVIDSON, M.D., F.A.C.P.Search for more papers by this author, LEONARD FOX, M.D.Search for more papers by this author, JAY J. GOLD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-4-852 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough a great deal of experimental work has been done on animals demonstrating the enhancing effect of ACTH and/or cortisone upon the evolution and development of tuberculous lesions,1-11 there are relatively few case reports in the literature dealing with this phenomenon in humans.12-19Presented in this report is a case of miliary tuberculosis, authenticated by postmortem examination, which developed during the course of extensive ACTH and cortisone therapy for acute disseminated lupus erythematosus.CASE REPORTA 49 year old single white female was admitted to the Jewish Hospital of Brooklyn for the first time on October 20, 1951, for joint...Bibliography1. 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SpainMolomut DMN: Effects of cortisone on the development of tuberculous lesions in the guinea pig and their modification by streptomycin therapy, Am. Rev. Tuberc. 62: 337, 1950. MedlineGoogle Scholar12. KingJohnsonBattenHenry EJGWL: Tuberculosis following cortisone therapy, J. A. M. A. 147: 238, 1951. CrossrefMedlineGoogle Scholar13. PoppOttosenBrasher CGPCA: Cortisone and pulmonary tuberculosis, J. A. M. A. 147: 241, 1951. CrossrefMedlineGoogle Scholar14. FredLevinRivoBarrett LMHJBTF: Development of active pulmonary tuberculosis during ACTH and cortisone therapy, J. A. M. A. 147: 242, 1951. CrossrefMedlineGoogle Scholar15. BogenNetzerSalkin ESD: Adrenocorticotropic and adrenocorticogenic hormones in tuberculosis, Transactions of the Tenth Conference on Chemotherapy of Tuberculosis, U. S. Veterans Administration, Atlanta, Ga., and Washington, D. C., 1951, p. 251. Google Scholar16. TompsettLeMaistreMuschenheimMcDermott RCCW: Effects of ACTH on tuberculosis in humans, J. Clin. Investigation 29: 849, 1950. MedlineGoogle Scholar17. LeMaistreTompsettMuschenheimMooreMcDermott CARCJAW: Effects of ACTH hormone and cortisone in patients with tuberculosis, J. Clin. Investigation 30: 445, 1951. CrossrefMedlineGoogle Scholar18. KleinschmidtJohnston RJ: Miliary tuberculosis in a cortisone treated patient, Ann. Int. Med. 35: 590, 1951. Google Scholar19. FreemanFershingWangSmith SJCCLC: Effect of ACTH on patients with pulmonary tuberculosis, Proceedings of First ACTH Conference, pp. 509-526, 1950. Google Scholar20. BermanAxelrodGoodmanMcClough LARHLRI: So-called lupus erythematosus inclusion phenomenon of bone marrow and blood, Am. J. Clin. Path. 20: 403, 1950. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication August 29, 1952.From the Department of Medicine, The Jewish Hospital of Brooklyn. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCase 48-1986Steroid therapy of systemic lupus erythematosus based on immunologic considerationsThe Effects of Drugs upon the EyeMiliary tuberculosis subsequent to trauma and simulating persistent intra-abdominal complicationsDie Corticoide in der Behandlung der LungentuberkuloseProphylaxis in patients receiving adrenal steroid therapyTuberculosis occurring in association with corticosteroid treatmentPulmonary tuberculosis following treatment with corticosteroidsPLEURITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS: ITS IMPORTANCE AS AN EARLY MANIFESTATION IN DIAGNOSIS*WILLIAM A. WINSLOW, M.D., LESTER N. PLOSS, M.D., BERNARD LOITMAN, M.D.RHEUMATISM AND ARTHRITIS REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (ELEVENTH RHEUMATISM REVIEW)* Part IIWILLIAM D. ROBINSON, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., WILLIAM S. CLARK, M.D., DARRELL C. CRAIN, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P. (C), MAX M. MONTGOMERY, M.D., F.A.C.P., BERNARD M. NORCROSS, M.D., F.A.C.P., CHARLES RAGAN, M.D., F.A.C.P., MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CHARLEY J. SMYTH, M.D., F.A.C.P.MILIARY TUBERCULOSIS DEVELOPING DURING PROLONGED CORTISONE THERAPY OF SYSTEMIC LUPUS ERYTHEMATOSUS*HAROLD M. HILL, M.D., J. D. KIRSHBAUM, M.D., F.A.C.P.TREATMENT OF A PATIENT WITH LUPUS ERYTHEMATOSUS AND PULMONARY TUBERCULOSIS WITH ACTH, STREPTOMYCIN AND PARA-AMINOSALICYLIC ACID*J. RICHARD JOHNSON, WINTHROP N. DAVEY, F.A.C.P. 1 April 1953Volume 38, Issue 4Page: 852-862KeywordsAdrenocorticotropic hormoneAutopsyHospital medicineLupus erythematosusMiliary tuberculosis ePublished: 1 December 2008 Issue Published: 1 April 1953 PDF downloadLoading ...