A 48-year-old woman with multiple pigmented skin lesions and a personal and family history of melanoma had been followed since the age of 32 in a clinic specializing in pigmented lesions. This Case Record reviews the classifications of familial mole and melanoma syndromes and discusses the role of genetic testing and the approach to management for this patient and her family.
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Tsao et al. (2004) studied this question.
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