Key result
Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome by mediating protective inflammation during weight gain.
Neuropilin-1 expression in adipose tissue macrophages plays a protective role against obesity and metabolic syndrome by mediating protective inflammation.
Should not yet inform obesity care; hypothesis-generating for neuropilin-1 targeting in animal models.
Neuropilin-1–expressing adipose tissue macrophages are critical mediators of protective inflammation during weight gain.
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Wilson et al. (2018) studied this question. Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome by mediating protective inflammation during weight gain.
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