Summary. Cyproterone acetate, a synthetic antiandrogenic steroid, caused a marked reduction in the weights of the accessory sex glands when given to male rats. The compound also affected the anterior lobe of the pituitary causing a decrease in the numbers of growth-hormone-producing cells. Cyproterone acetate did not inhibit spermatogenesis and the Leydig cells were normal.
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Lakshman et al. (1973) studied this question.
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