Key result
Endovascular treatment for abdominal aortic aneurysm repair had similar 30-day mortality compared to open surgery (4.1% vs. 5.0%; p=0.78), with less bleeding and shorter hospital stays.
Why the study?
Does endovascular treatment compared to open surgery improve clinical outcomes in patients with abdominal aortic aneurysm?
Cohort (n=338)
No
Does endovascular treatment compared to open surgery improve clinical outcomes in patients with abdominal aortic aneurysm?
Endovascular repair of abdominal aortic aneurysms offers similar 30-day mortality to open surgery but significantly reduces intraoperative bleeding and hospital length of stay, albeit at a higher cost.
Answers are grounded in this paper and cite their sources.
Endovascular repair may reduce perioperative morbidity in observational cohorts; leaves open need for RCTs on long-term outcomes.
Context:Abdominal aortic aneurysm (AAA) is a condition that is usually asymptomatic, but potentially fatal, and has a prevalence in men over 60 years old ranging from 4.3% to 8%. There are two treatment options available: open surgery (OS) and endovascular treatment (ET).Objective:To compare the results of repairs conducted using these two treatment methods from 2008 to 2013 in a tertiary hospital.Methods:A retrospective analysis comparing 119 patients treated with OS and 219 patients who underwent ET for AAA repair.Results:The ET group was older (71.3 vs. 68.2 years; p<0.001) and had a higher rate of coronary disease (44.7% vs. 27.7%; p=0.002) and a lower ejection fraction (57.6% vs. 64.3%; p<0.001); in turn, the OS group had more chronic obstructive pulmonary disease (16.0% vs. 5.9%; p=0.004) and a smaller proximal infrarenal neck (15.5 mm vs. 23.0 mm; p<0.001). However, there was no difference in ASA classification (American Society of Anesthesiology) (p=0.36). The ET group had less intraoperative bleeding (171 mL vs. 729 mL; p<0.001) and required fewer blood transfusions (11.9% vs. 73.1% p<0.001), and spent shorter stays in both ICU (2.4 vs. 3.5 days; p=0.002) and hospital (5.8 vs. 10.3 days; p<0.001). Thirty-day mortality was similar (OS 5.0% vs. ET 4.1%; p=0.78) and there was also no difference in postoperative complications. The average cost of ET was higher (R$34,277.76 vs. R$4,778.60; p<0.001).Conclusions:Rates of morbidity and mortality were similar, although ET was associated with less bleeding, fewer transfusions and shorter hospital stays, but was more expensive.
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Miranda et al. (2014) conducted a cohort in Abdominal aortic aneurysm (AAA) (n=338). Endovascular treatment vs. Open surgery was evaluated on Thirty-day mortality (p=0.78). Endovascular treatment for abdominal aortic aneurysm repair had similar 30-day mortality compared to open surgery (4.1% vs. 5.0%; p=0.78), with less bleeding and shorter hospital stays.
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