Key result
Endovascular aneurysm repair in elderly patients requires appropriate risk-stratification to determine who will benefit, given higher mortality and lack of long-term longevity gains.
Why the study?
Does endovascular aneurysm repair (EVAR) benefit elderly patients with supra-threshold aortic aneurysms compared to open surgery?
Does endovascular aneurysm repair (EVAR) benefit elderly patients with supra-threshold aortic aneurysms compared to open surgery?
There is a critical need for appropriate risk-stratification in elderly patients considered for EVAR due to higher mortality, complications, and negative impacts on quality of life.
Risk-stratification remains essential before EVAR in elderly patients; leaves open the need for prospective data on long-term outcomes versus open repair.
Endovascular aneurysm repair (EVAR) has become the intervention of choice for supra-threshold aortic aneurysms due to the lower 30-day mortality of EVAR as compared with open surgery, despite no long-term longevity gains. Trials such as EVAR-1 that established the current status of endovascular aortic intervention often excluded participants over the age of 80, and specific studies of EVAR in the elderly reveal higher mortality than accepted averages. Analyses of the cost-effectiveness of EVAR have not demonstrated superiority of endovascular intervention over open repair, in particular when considering complications such as endoleak. Post-intervention surveillance and the frequent need for re-intervention following EVAR has a detrimental impact on quality of life. Taking these factors into consideration, combined with an ageing population and the likely increase in octogenarian endovascular intervention, there is a clear clinical need for appropriate risk-stratification of elderly patients with supra-threshold aneurysms to determine who will benefit from endovascular repair.
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Qureshi et al. (2017) conducted a review in Supra-threshold aortic aneurysms in the elderly. Endovascular aneurysm repair (EVAR) vs. Open surgery was evaluated. Endovascular aneurysm repair in elderly patients requires appropriate risk-stratification to determine who will benefit, given higher mortality and lack of long-term longevity gains.
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