Key result
Ketamine and lidocaine infusions are being studied as non-opioid adjuvants to manage acute postoperative pain and limit opioid side effects after elective open abdominal surgery.
Why the study?
Postoperative pain management remains challenging, and opioid side effects limit their use, prompting the evaluation of adjuvant and alternative non-opioid drugs.
Does ketamine and lidocaine infusion improve acute pain in patients undergoing elective open abdominal surgery?
Does ketamine and lidocaine infusion improve acute pain in patients undergoing elective open abdominal surgery?
Supports ketamine-lidocaine infusion to cut early pain and analgesic needs after open abdominal surgery; extends RCT evidence for non-opioid adjuvants.
↑What is "already known" in this topic:Postoperative pain management is one of the most challenging issues for clinicians.Although opioids are the most commonly used for this points, its side effects limit their use in some cases.For this purpose, adjuvant and alternative non-opioid drugs have been studied. →What this article adds:Ketamine and lidocaine are non-opioid drugs that have some analgesic effects.The combination of these two drugs, without the side effects of opioids, may have appropriate analgesic effects for postoperative pain after abdominal surgeries.
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Imani et al. (2022) studied this question. Ketamine and lidocaine infusions are being studied as non-opioid adjuvants to manage acute postoperative pain and limit opioid side effects after elective open abdominal surgery.
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