A study of the biosynthesis of the tripeptide δ-( l -α-aminoadipyl)- l -cysteinyl- d -valine in a β-lactam-negative mutant of Cephalosporium acremonium

A cell-free extract of Cephalosporium acremonium (Takeda N-2) was obtained that synthesized the tripeptide delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine and also the dipeptide delta-(L-alpha-aminoadipyl)-L-cysteine from the corresponding L-amino acids.