Dimorphism-associated changes in amino acid transport ofCandida albicans

Amino acid uptake was followed during pHregulated dimorphism of Candida albicans.It was observed that transport activities of various amino acids differed with the morphological phenotype.The uptake rates of L-alanine, L-phenylalanine and of L-lysine were lower and those of Lmethionine were higher in elongated hypha (germ tube), while the rates of glycine, L-glutamic acid and L proline were similar in bud and hyphal phenotypes.Minimum threshold of amino acids transport activity is required at the time of phenotypic commitment in a diverging population of Candida albicans.