Key result
Transradial access for primary percutaneous coronary intervention in STEMI patients significantly reduced major access site complications compared to transfemoral access (0% vs 5%, p<0.001) with similar procedural success.
Why the study?
Does transradial primary PCI reduce complications compared to transfemoral primary PCI in patients with STEMI?
Cohort (n=352)
No
Does transradial primary PCI reduce complications compared to transfemoral primary PCI in patients with STEMI?
Transradial access for primary PCI in STEMI is feasible and significantly reduces major access site complications compared to transfemoral access.
Answers are grounded in this paper and cite their sources.
May favor transradial access to reduce complications in STEMI primary PCI; leaves open need for randomized confirmation before practice change.
We aimed to evaluate the feasibility of transradial primary percutaneous coronary intervention (PCI) in patients with ST elevation myocardial infarction (STEMI) by comparing the procedural results and complications with those of transfemoral intervention. From April 1997 to October 2004, we enrolled 352 consecutive cases of STEMI who underwent primary PCI. The femoral route was used in 132 cases (TFI group) and the radial route was used in 220 cases (TRI group). Cases with Killips class IV, a negative Allen test or a non-palpable radial artery were excluded from our study. Baseline clinical and angiographic profiles were comparable in both groups. Vascular access time was 3.8 +/- 3.5 min in the TFI group and 3.6 +/- 3.1 min in the TRI group, and cath room to reperfusion time was 25 +/- 11 min in the TRI group and 26 +/- 13 min in the TRI group. The procedural success rate was 89% in the TFI group and 88% in the TRI group. Crossover occurred in 9 cases (4%) due to approaching vessel tortuosity in the TRI group. Major access site complications occurred in 7 cases (5%) in the TFI group, and there were no complications in the TRI group (p < 0.001). Although radial occlusion occurred in 5 cases of the TRI group, there was no evidence of hand ischemia. The total hospital stay was significantly shorter in TRI group than in TFI group. In conclusion, use of the radial artery might be a potential vascular access route in performing primary PCI in selected cases.
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Kim et al. (2005) conducted a cohort in ST elevation myocardial infarction (STEMI) (n=352). Transradial intervention (TRI) vs. Transfemoral intervention (TFI) was evaluated on Major access site complications (p=<0.001). Transradial access for primary percutaneous coronary intervention in STEMI patients significantly reduced major access site complications compared to transfemoral access (0% vs 5%, p<0.001) with similar procedural success.
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