A total of 86 patients with extrahepatic bile duct cancer (excluding intraduodenal bile ducts and the ampulla of Vater) selected from 422 patients with cancer of the biliopancreatoduodenal region were studied clinicopathologically. Significant parameters influencing the prognosis include histologic grade of differentiation, lymph node metastasis, perineural invasion, and immunohistochemical demonstration of carcinoembryonic antigen (CEA). Tumor cells had CEA, carbohydrate antigen 19‐9 (CA19‐9),and c‐Ha‐ras p21 antigen (p21) reactants in 75, 58, and 20 patients, respectively, of the 82 patients with bile duct cancer. Four tumors were classified as early bile duct cancers, showing a polypoid mass restricted within the bile duct wall. The patients with such early carcinoma were alive with the postoperative course ranging from 1 1/2 to 7 1/2 years.
No takes yet. Share an insight, caveat, or question.
Yamaguchi et al. (1988) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: