Anorexigenic Agents

ANOREXIGENIC agents may be defined as substances that tend to suppress appetite or hunger sensation or both. Such agents, which are employed therapeutically for the purpose of inducing weight reduction, may influence primarily either central or peripheral mechanisms concerned with food intake. The latter mechanisms are affected by a group of compounds designed to mask the sensation of hunger reflexly by elevating blood sugar, inhibiting vagal activity or otherwise depressing gastric motility (thus inducing a sensation of satiety), or by providing intestinal bulk. This approach, neither very effective nor always free of undesirable side reactions, has not received the universal . . .