The coexistence of pemphigus and Hodgkin's disease has not previousiy been reported. We observed a patient who developed pemphigus vulgaris nearly 2 years after Hodgkin's disease had been found to be present, Subsequently the diseases ran a parallel course in three relapses and remissions. The remissions were induced by cyclophosphamide. The possibility that Hodgkin's disease predisposed the patient to pemphigus is considered in view of the recent postulate that thymus‐dependent lymphocytes prevent the development of autoimmunity, and that the diseases associated with depression of cell mediated immunity can lead to the development of autoimmune phenomena.
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SOOD et al. (1974) studied this question.
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