Crazy-Paving Pattern: A Rare Case of Autoimmune Pulmonary Alveolar Proteinosis (PAP) with Positive Anti-GM-CSF Antibody Following Cryptococcal Infection in an otherwise Healthy Individual and Review of Literature

Pulmonary alveolar proteinosis (PAP) is a rare disease characterised by accumulation of lipoproteinaceous material composed principally of surfactant phospholipid and apoproteins within the alveoli, resulting in impairment of gas exchange It was first described by Rosen et al. in 1958 [1]. There is a wide range of clinical manifestation of PAP ranging from respiratory failure to spontaneous resolution.