Key result
Patients with 5 or 6 perioperative risk factors were 101 times more likely to develop colonic ischemia after ruptured abdominal aortic aneurysm repair compared to those with 0 to 4 factors (P<.001).
Why the study?
Does selective surveillance colonoscopy based on perioperative risk factors reliably diagnose colonic ischemia in patients after successful ruptured abdominal aortic aneurysm repair?
Cohort (n=62)
Does selective surveillance colonoscopy based on perioperative risk factors reliably diagnose colonic ischemia in patients after successful ruptured abdominal aortic aneurysm repair?
Selective surveillance colonoscopy based on the presence of more than three perioperative risk factors can reliably diagnose colonic ischemia early after successful ruptured abdominal aortic aneurysm repair.
May support risk-stratified colonoscopy after rAAA repair; leaves open prospective validation before practice change.
PURPOSE: To evaluate the reliability of selective surveillance colonoscopy based on 6 specific perioperative risk factors in the early diagnosis of colonic ischemia (CI) after successful ruptured abdominal aortic aneurysm (rAAA) repair. PATIENTS AND METHODS: From 1999 to 2005, 62 consecutive patients underwent rAAA repair. In 59 of them, routine aggressive surveillance colonoscopy was offered every 12 hours within the first 48 hours, and CI was graded consistently. Patients with stage I or stage II CI were treated conservatively and were followed up with repeat colonoscopy, whereas patients with stage III CI underwent immediate laparotomy and colectomy. In parallel, 6 specific perioperative risk factors (PRFs) were retrospectively analyzed. RESULTS: Overall mortality was 33.9%. Nineteen patients (32.2%) developed CI and 12 (63.2%) of them survived. Thirteen (22%) had grade III CI and among these 6 survived. In patients with CI the mortality rate was 36.2%. Patients with less than 3 PRFs had no CI whereas all instances of CI could be diagnosed if colonoscopy was offered selectively in patients with more than 3 PRFs. The positive predictive value of CI increased with the number of PRFs. Patients with 5 or 6 PRFs were about 101 times more likely to develop CI compared with patients with 0 to 4 PRFs (P<.001). CONCLUSION: Our study showed that CI is a frequent complication after successful rAAA repair and could reliably be early diagnosed if surveillance colonoscopy was offered selectively in patients with more than three PRFs.
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Megalopoulos et al. (2007) conducted a cohort in Ruptured abdominal aortic aneurysm (rAAA) (n=62). 5 or 6 perioperative risk factors vs. 0 to 4 perioperative risk factors was evaluated on Colonic ischemia (OR 101, p=<.001). Patients with 5 or 6 perioperative risk factors were 101 times more likely to develop colonic ischemia after ruptured abdominal aortic aneurysm repair compared to those with 0 to 4 factors (P<.001).
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