August 1, 1987Journal of Neurology Neurosurgery & PsychiatryOpen Access

Muscle fibre type composition, motoneuron firing properties, axonal conduction velocity and refractory period for foot extensor motor units in dystrophia myotonica.

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Population

7 patients with dystrophia myotonica

Comparison

Neurophysiological and histochemical… vs Healthy subjects

Design

Cross-sectional

Authors

JBJörgen BorgKarolinska Institutet LELars EdströmUppsala University GBGillian Butler‐BrowneInserm

Discussion

Member takes

Implication

Supports abnormal regeneration in myotonic dystrophy motor units; hypothesis-generating and should not yet change practice.

Structured PICO

Population

7 patients with dystrophia myotonica

Intervention

Neurophysiological and histochemical investigation of foot extensor muscles

Comparator

Healthy subjects

Outcome

Motor unit properties (axonal conduction velocity, refractory period, firing properties) and muscle fibre type compositionsurrogate

Patients with dystrophia myotonica exhibit reduced axonal conduction velocity and a reduced proportion of type II motor units in foot extensor muscles, indicating abnormal regeneration or fibre transformation.

Cite This Study

Borg et al. (1987) studied this question.

synapsesocial.com/papers/6a946dc87779db04076e5703 https://doi.org/10.1136/jnnp.50.8.1036

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Muscle fibre type composition, motoneuron firing properties, axonal conduction velocity and refractory period for foot extensor motor units in dystrophia myotonica.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Muscle fibre type composition, motoneuron firing properties, axonal conduction velocity and refractory period for foot extensor motor units in dystrophia myotonica.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider