OBJECTIVE: To determine the relationship between the change in middle cerebral artery peak systolic velocity (MCA-PSV) and the change in fetal Hemoglobin (Hb) immediately following intrauterine transfusion (IUT). MATERIALS AND METHODS: Study data included all IUTs performed for suspected fetal anemia from 2007-2011. RESULTS: Sixty-eight IUTs were performed for 23 pregnancies, demonstrating a statistically significant MCA-PSV decrease for up to four IUTs. Significant correlations between changes in Hb levels and MCA-PSV were not detected. CONCLUSION: MCA-PSV values were highly variable in the immediate post-operative period and did not correlate with the Hb change.
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Grubbs et al. (2012) studied this question.
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