Mixed Anaplastic Small-Cell and Squamous-Cell Carcinoma of the Lung

and the appearance of histologically well and poorly dif-ferentiated areas within a tissue specimen, or even the coexistence of multiple discreet histologic subtypes, is not uncommon. The association, however, of small-cell ana-plastic and squamous-cell lung cancer has been rarely noted, and we report here a 24 % prevalence of this asso-ciation in an autopsy series. Fifty consecutive previously untreated patients with biopsy-proven small-cell carcinoma of the lung were studied between