Quite simply, the 1983 article by Moertel on the treatment of the carcinoid tumor and the malignant carcinoid syndrome in the first volume of Journal of Clinical Oncology is brilliant. It is full of clinical pearls that ring as true today as when the article was written. I had the privilege and the pleasure of working with Dr Moertel for 18 years at the Mayo Clinic. This editorial will review the continuing evolution of oncology research in the field and highlight how the science has changed in the “land of small tumors” over the last 25 years.
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Larry K. Kvols (2008) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: