Key result
General fatigue accounted for 68.5% of the variation in vitality among post-polio patients, with physiological indicators explaining 91% of this variance.
Cross-Sectional (n=143)
Yes
Effect estimate: R2 0.685
p-value: p=<0.001
Vitality in post-polio patients is primarily dependent on physiological rather than psychological parameters, suggesting clinical focus should be on physical fatigue and symptom management.
May warrant physiological focus in post-polio vitality assessment; hypothesis-generating, requires prospective trials before practice implications.
OBJECTIVE: To evaluate vitality and fatigue in post-polio patients, and the relative contributions of physiological and psychological parameters to the level of vitality. DESIGN: Multi-centre study. SUBJECTS: One hundred and forty-three patients with post-polio syndrome. METHODS: Inventories of background, quality of life, fatigue and sleep quality were used. Pain was evaluated using a visual analogue scale. Descriptive statistics and correlations were used for all selected parameters. Hierarchical regression models were constructed to examine predictors of variations in vitality, pain, reduced activity and physical fatigue. RESULTS: General fatigue accounted for 68% of the variation in vitality. Of this, 91% was accounted for by physiological indicators. After controlling for age, physiological para notmeters accounted for 56.6% and 25%, if entered before and after the psychological parameters, respectively. The impact of the psychological parameters decreased after accounting for the physiological parameters. Physical fatigue, age and sleep quality were associated with variation in pain. Body mass index, pain and sleep quality accounted for differences in reduced activity and physical fatigue. CONCLUSION: Vitality in post-polio patients depends on physio-logical parameters. Mental fatigue is not a prominent predictor. Subgroups with or without fatigue, independent of age, need further study.
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Östlund et al. (2008) conducted a cross-sectional in Post-polio syndrome (n=143). Physiological and psychological parameters was evaluated on Variance in vitality accounted for by general fatigue (R2 0.685, p=<0.001). General fatigue accounted for 68.5% of the variation in vitality among post-polio patients, with physiological indicators explaining 91% of this variance.
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