Dexamethasone may provide rapid resolution of acute superior vena cava obstruction developing shortly after chemotherapy.
Dexamethasone may offer rapid relief in acute post-chemotherapy SVC obstruction; single case leaves open need for prospective validation.
Superior vena cava obstruction developed a few hours after the administration of chemotherapy for small-cell lung carcinoma. The syndrome responded rapidly to dexamethasone. Although the mechanisms of the appearance and resolution of the superior vena cava obstruction in this patient remain hypothetic, there is an important therapeutic implication.
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Julien J. Sand (1985) studied this question.
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