Key result
A 32-year-old female carrier of a homozygous type II (L99F) antithrombin deficiency with a history of deep vein thrombosis had a successful pregnancy outcome.
Case Report (n=1)
Reports a successful pregnancy outcome in a rare case of homozygous type II (L99F) antithrombin deficiency, adding to the limited literature on pregnancy management in this condition.
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May inform counseling in rare antithrombin deficiency pregnancies; leaves open optimal protocols pending systematic data.
Inherited antithrombin deficiency is associated with an increased risk of venous thromboembolism. There is no consensus about pregnancy management in antithrombin deficiency patients because there are very few cases published in the literature. We report a successful pregnancy in a 32-year-old female carrier of a homozygous type II (L99F) antithrombin deficiency who developed a spontaneous deep vein thrombosis at the age of 27 years.
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Pascual et al. (2013) conducted a case report in Homozygous type II (L99F) antithrombin deficiency in pregnancy (n=1). Pregnancy was evaluated on Pregnancy outcome. A 32-year-old female carrier of a homozygous type II (L99F) antithrombin deficiency with a history of deep vein thrombosis had a successful pregnancy outcome.
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