Key result
Peroperative episodes of myocardial ischemia during non-cardiac surgery were associated with postoperative left ventricular dysfunction in patients with angina pectoris.
Why the study?
Does peroperative myocardial ischemia during non-cardiac surgery cause postoperative left ventricular dysfunction in patients with angina pectoris?
Observational (n=20)
Does peroperative myocardial ischemia during non-cardiac surgery cause postoperative left ventricular dysfunction in patients with angina pectoris?
Peroperative myocardial ischemia during non-cardiac surgery is associated with the development of postoperative left ventricular dysfunction in patients with angina pectoris.
In order to demonstrate the presence of postischemic ventricular dysfunction after non-cardiac surgical procedures, myocardial perfusion scintigraphy with thallium 201 and radionuclide ventriculography were performed before and 24 h after intervention in 20 patients suffering from angina pectoris. A long-term ECG recording was used in all patients to detect peroperative myocardial ischemia. In 14 of the 20 patients studied, both ventriculography and thallium scintigraphy were unchanged at the postoperative study. Comparison of pre- and postoperative radionuclide data revealed an increased deficit in one patient, both increased deficit and decreased ejection fraction in four others and a decreased ejection fraction in one other. In these five last patients, continuous ECG recording demonstrated the occurrence of peroperative ST segment depression. These results underline the part played by prolonged peroperative episodes of myocardial ischemia in the occurrence of postoperative left ventricular dysfunction.
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Coriat et al. (1985) conducted an observational in Ischemic Heart Disease (angina pectoris) (n=20). Peroperative myocardial ischemia during non-cardiac surgery vs. Absence of peroperative myocardial ischemia was evaluated on Postoperative left ventricular dysfunction (increased deficit or decreased ejection fraction). Peroperative episodes of myocardial ischemia during non-cardiac surgery were associated with postoperative left ventricular dysfunction in patients with angina pectoris.
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