Hypertrophic Osteoarthropathy in Pulmonary Malignancies

Article1 February 1953HYPERTROPHIC OSTEOARTHROPATHY IN PULMONARY MALIGNANCIESEDWARD S. RAY, M.D., F.A.C.P., HUGH P. FISHER JR., M.D.EDWARD S. RAY, M.D., F.A.C.P.Search for more papers by this author, HUGH P. FISHER JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-2-239 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONHypertrophic osteoarthropathy has interested internists since the latter part of the Nineteenth Century, when Marie1 and Bamberger2 independently reported the presence of osteitis of the long bones of the extremities associated with pulmonary disease. Since that time, similar bone changes have been reported in many disease processes.Although chronic pulmonary disease3, 4, 5, 6, 7has been the most frequent cause of osteoarthropathy, these bone changes have been frequently noted in cases of congenital heart disease,4, 13arteriovenous fistula and subacute bacterial endocarditis14; less frequently it has been described in cases of chronic liver disease,4chronic infections of the...Bibliography1. Marie P: De l'osteo-arthropathie hypertrophiante pneumique, Rev. de méd., Paris 10: 1-36, 1890. Google Scholar2. Bamberger E: Ueber Knochenveränderungen bei chronischen Lungen- und Herzkrankheiten, Ztschr. f. klin. Med. 18: 193, 1891. Google Scholar3. Berg R: Arthralgia as a first symptom of pulmonary lesions, Dis. of Chest 16: 483, 1949. CrossrefMedlineGoogle Scholar4. Cushing EH: Clubbed fingers and hypertrophic pulmonary osteoarthropathy, Internat. Clin. 2: 200, 1937. Google Scholar5. 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HebrantLiegedis AO: Bull. Acad. roy. de méd. de Belgique 8: 275, 1928. Google Scholar21. BallAlamartine VH: Tuberculose inflammatoire et ostéo-arthropathies hypertrophiantes pneumiques, Gaz. d. hôp., Paris 85: 1587-1590, 1912. Google Scholar22. WissingWeiss EGL: Unusual case of pulmonary osteoarthropathy in a dog, Am. J. Roentgenol. 50: 527, 1943. Google Scholar23. CampbellSacasaCamp DCCFJD: Chronic hypertrophic osteoarthropathy, Proc. Staff Meet., Mayo Clin. 13: 708, 1938. Google Scholar24. Mauer EF: On etiology of clubbing of the fingers, Science 104: 555, 1946. CrossrefMedlineGoogle Scholar25. Fried BM: Chronic pulmonary osteoarthropathy; dispituitarism as a probable cause, Arch. Int. Med. 72: 565, 1943. CrossrefGoogle Scholar26. Bloom W: Pituitary implications in hypertrophic pulmonary osteoarthropathy, Ann. Int. Med. 29: 361, 1948. LinkGoogle Scholar27. PattisonBeckMiller JDEWB: Hypertrophic osteoarthropathy in carcinoma of the lung, J. A. M. A. 146: 783, 1951. CrossrefMedlineGoogle Scholar28. Cabot Case 34481, New England J. Med. 239: 834, 1948. CrossrefMedlineGoogle Scholar29. Cabot Case 31271, New England J. Med. 233: 18, 1945. CrossrefGoogle Scholar30. Fischl JR: Severe hypertrophic pulmonary osteoarthropathy, Am. J. Roentgenol. 64: 42, 1950. Google Scholar31. TempleJaspin NLG: Hypertrophic osteoarthropathy, Am. J. Roentgenol. 60: 232, 1948. Google Scholar32. HolmesBaumanRagan HHEC: Symptomatic arthritis due to hypertrophic osteoarthropathy in pulmonary neoplastic disease, Ann. Rheumat. Dis. 9: 169, 1950. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Richmond, Virginia*Received for publication September 10, 1952.From the Department of Medicine, Medical College of Virginia Hospital, and Medical Service, McGuire Veterans Administration Hospital, Richmond, Virginia.Sponsored by the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration. 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ROBINSON, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., WILLIAM S. CLARK, M.D., DARRELL C. CRAIN, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P. (C), MAX M. MONTGOMERY, M.D., F.A.C.P., BERNARD M. NORCROSS, M.D., F.A.C.P., CHARLES RAGAN, M.D., F.A.C.P., MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CHARLEY J. SMYTH, M.D., F.A.C.P.URINARY EXCRETION OF ŒSTROGENSLUNGS, BONES, AND JOINTSCYCLICAL VOMITINGLUNGS, BONES, AND JOINTSDie Ost�oarthropathie hypertrophiante pneumiqueDiagnostic significance of pulmonary hypertrophic osteoarthropathyLung Lesions in ArthritisDiscussion: Unusual Manifestations of Bronchial Carcinoma 1 February 1953Volume 38, Issue 2Page: 239-246KeywordsBacterial diseasesBoneChronic liver diseaseEndocarditisFistulasHeartHospital medicineInfectious diseasesMedical servicesPulmonary diseases ePublished: 1 December 2008 Issue Published: 1 February 1953 PDF downloadLoading ...