The study demonstrates high prevalence of enterovirus excretion in a residential nursery and suggests potential interference between Coxsackie B and polioviruses, which may impact poliovirus vaccination efficacy.
A longitudinal study of illness and prevalence of enteroviruses was carried out in a Trinidad residential nursery. 92 enteroviruses (46 strains of Coxsackie B virus and 46 of poliovirus) were recovered from 233 faecal specimens (39·5%). The percentage of children who excreted viruses at any one time rose from 48% to 90%, being related to the number of specimens examined from each child. Apparent interference between Coxsackie B viruses and polioviruses was observed and the significance of this in relation to poliovirus vaccination is discussed.
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Sutton et al. (1967) studied this question.
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