Key result
The incidence of pacemaker-induced cardiomyopathy in patients with right ventricular pacing ranged from 10.7% to 13.7%, with preimplantation LVEF, interventricular dyssynchrony, and RV pacing burden identified as predictors.
Why the study?
The incidence and predictors of pacemaker-induced cardiomyopathy in patients with right ventricular pacing needed to be determined.
Systematic Review (n=1,365)
In patients with right ventricular pacing, the incidence of pacemaker-induced cardiomyopathy is approximately 10.7% to 13.7%, driven by predictors such as RV pacing burden, preimplantation LVEF, and interventricular dyssynchrony.
Answers are grounded in this paper and cite their sources.
Supports monitoring for PICM in patients with low preimplantation LVEF or high RV pacing burden; extends meta-analytic confirmation of incidence and predictors.
This study aimed to figure out the incidence and predictors of pacemaker-induced cardiomyopathy (PICM) in patients with right ventricular (RV) pacing. We systematically searched in PubMed on March 18, 2020, for English language abstract and full-article journals, using the following criteria: pacemaker induced cardiomyopathy AND right ventricular AND pacemaker AND patients AND human NOT implantable cardioverter defibrillator NOT ICD NOT animal. Four studies were included in this review after filtering 35 studies through year of publication and abstract selection. The average PICM incidence from 1,365 patients included from the four studies was 10.7 to 13.7%. One study stated that preimplantation left ventricular ejection fraction (LVEF) was the predictor for the development of PICM. Three studies mentioned that RV pacing burden was the predictor for the development of PICM. However, the percentage differ in three studies: ≥20, >40, and 60%. In addition, one of the studies also included interventricular dyssynchrony as another predictor. The incidence of PICM in patients with RV pacing ranged from 10.7 to 13.7%. Preimplantation LVEF, interventricular dyssynchrony, and burden of RV pacing are reported as the predictors for the development of PICM in patients with RV pacing.
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Laksono et al. (2021) conducted a systematic review in Right ventricular pacing (n=1,365). Right ventricular pacing was evaluated on Incidence of pacemaker-induced cardiomyopathy (PICM) (10.7% to 13.7% incidence). The incidence of pacemaker-induced cardiomyopathy in patients with right ventricular pacing ranged from 10.7% to 13.7%, with preimplantation LVEF, interventricular dyssynchrony, and RV pacing burden identified as predictors.
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