What question did this study set out to answer?

To determine whether cardiopulmonary bypass utilizing pulsatile flow improves regional blood flow in the liver, pancreas, and kidney compared with nonpulsatile flow during profound hypothermia and total circulatory arrest.

January 1, 1988Japanese Circulation Journal-english EditionOpen Access

Regional blood flow in the liver, pancreas and kidney during pulsatile and nonpulsatile perfusion under profound hypothermia.

View Full Paper

Ask AI

Bookmark

Authors

AMAtsumi MoriTokyo Medical and Dental University KWK Watanabe MOMasahiko OnoeKishiwada City Hospital

Discussion

Member takes

Implication

Experimental study demonstrates pulsatile perfusion preserves visceral blood flow during hypothermic circulatory arrest in canines, indicating superior organ protection over nonpulsatile flow.

Key Points

To determine whether cardiopulmonary bypass utilizing pulsatile flow improves regional blood flow in the liver, pancreas, and kidney compared with nonpulsatile flow during profound hypothermia and total circulatory arrest.
Conducted total cardiopulmonary bypass in 56 adult mongrel dogs to induce profound hypothermia.
Subjected animals to 40 minutes of total circulatory arrest at 20°C followed by rewarming to 35°C under pulsatile or nonpulsatile flow.
Measured regional blood flow in the liver, pancreas, and kidney before, during, and after total circulatory arrest.
Pulsatile flow prevented drops in regional blood flow to the liver, pancreas, and kidney during cooling, particularly at 20°C prior to total circulatory arrest.
Renal blood flow recovered rapidly following total circulatory arrest with pulsatile flow.
Nonpulsatile flow after circulatory arrest resulted in undetectable cortical blood flow and significantly reduced medullary blood flow in the kidneys.

Cite This Study

Mori et al. (1988) studied this question.

synapsesocial.com/papers/6a9482676360e5bcdda25f36 https://doi.org/10.1253/jcj.52.219

View Full Paper

Ask AI

Bookmark

Implication

Experimental study demonstrates pulsatile perfusion preserves visceral blood flow during hypothermic circulatory arrest in canines, indicating superior organ protection over nonpulsatile flow.

Regional blood flow in the liver, pancreas and kidney during pulsatile and nonpulsatile perfusion under profound hypothermia.

Discussion

Member takes

Implication

Key Points

Cite This Study

Regional blood flow in the liver, pancreas and kidney during pulsatile and nonpulsatile perfusion under profound hypothermia.

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider