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A review of the clinical and histological features of pustulosis palmaris et plantaris (PPP) was undertaken. The morphologic development of PPP is biphasic: the first phase consists of an eczematous reaction, and the second phase is the pustulation of eczematous vesicles. PPP may be aggravated by infections or non-infectious inflammatory processes elsewhere in the body. An abnormal glucose tolerance test was found in 55 (66.3%) of 83 patients with PPP. The deranged carbohydrate metabolism may be partly responsible for the increased susceptibility to focal infections in patients with PPP.
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Masami Uehara (1983) studied this question.
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