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January 1, 1999Synthesis

A Practical Method for the Preparation of Nitriles from Primary Amides Under Non-Acidic Conditions

D. Subhas Bose Basavegowda Jayalakshmi

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Abstract

All articles of this category In order to establish a mild conversion method of primary amides to nitriles, various types of carboxamides were treated with trifluoromethanesulfonic anhydride and triethylamine, as a dehydrating agent to obtain the desired nitriles in 84-95% yields. trifluoromethanesulfonic anhydride - carboxamides - dehydration

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Cite This Study

Bose et al. (1999) studied this question.

synapsesocial.com/papers/6a94c784e1afc3c5b2430994 https://doi.org/10.1055/s-1999-3695

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