Getting round the (periodic) table: The enamine activation concept has been extended to the asymmetric addition of selenium-based compounds to aldehydes in an organocatalytic transformation that provides high reaction efficiency and stereocontrol (ee values ranging from 95 to 99 %) with readily available chiral secondary amines. The chiral α-seleno aldehydes thus formed can be used as versatile intermediates .
No takes yet. Share an insight, caveat, or question.
Tiecco et al. (2007) studied this question.