Synthetic study demonstrates rapid catalytic generation of alpha-azidoketones and alpha-thiocyanatoketones from aryl ketones, highlighting an efficient approach avoiding intermediate isolation.
Iodobenzene‐catalyzed synthesis of α‐azidoketones and α‐thiocyanatoketones from aryl ketones with MCPBA as a cooxidant is described. The method is simple, rapid and practical, generating α‐azidoketones and α‐thiocyanatoketones from the aryl ketone without isolation of α‐tosyloxyketones in good to excellent yields.
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Chang et al. (2010) studied this question.
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