Complete stereodivergence in the synthesis of 2-amino-1,3-diols from allenes

This is the authors' abstract. We don't add key points for this paper.

Herein, we describe studies to understand how both reagent and substrate control can be effectively employed in the stereodivergent oxidative amination of allenes, with transfer of the axial chirality of an enantioenriched precursor to point chirality in each possible diastereomeric 2-amino-1,3-diol product.