Synthesis and 1H‐, 13C‐NMR analysis of some substituted 1,2,3,4‐tetrahydroisoquinolines

Synthesis and 1H‐, 13C‐nmr analysis of some substituted 3‐phenyl‐1,2,3,4‐tetrahydroisoquinolines are reported. Spectroscopy assignments of hydrogen and carbon resonances were made on the basis of standard chemical shift theory, comparison with reference compounds, attached proton test and fully coupled 13C‐nmr spectra. Data showed that at room temperature two conformers predominated for the 1,3‐disubstituted and 1,2,3‐trisubstituted isoquinolines.