Key result
Surgical resection followed by chemoradiotherapy resulted in no tumor recurrence and normal motor function at 9 months postoperatively in a patient with primary parasagittal meningeal angiosarcoma.
Why the study?
Intracranial meningeal angiosarcoma is extremely rare, with only 8 cases previously reported and no large-sample clinical studies available.
Case Report (n=1)
No
Intracranial meningeal angiosarcoma is a rare tumor that requires surgical resection and immunohistochemistry for accurate diagnosis, with extensive superficial hemosiderin deposition being a potential intraoperative diagnostic clue.
This is the authors' abstract. We don't add key points for this paper.
BACKGROUND: Angiosarcoma, also known as malignant hemangioendothelioma, is a rare vasogenic malignant tumor, commonly found on the skin of the head and neck, rarely occurring in the intracranial region. As for intracranial meningeal angiosarcoma, only 8 cases have been reported before and there is no clinical study with large sample size. We report here a case of parasagittal meningeal angiosarcoma. CASE DESCRIPTION: A 48-year-old Chinese male patient was admitted to our hospital due to headache accompanied by bilateral lower limb weakness. On admission, CT showed a high-density mass on both sides of the sagittal sinus at the top of the frontal lobe. We performed exploratory surgical resection of the tumor. During the operation, it was found that the tumor originated from the dura mater and extensively invaded the surrounding brain tissue and skull, and the surrounding hemosiderin deposition was observed. Postoperative pathology suggested angiosarcoma. CONCLUSIONS: Intracranial meningeal angiosarcoma is difficult to accurately diagnose before surgery, so radiologists and neurosurgeons need to strengthen their understanding of this disease. The presence of extensive superficial hemosiderin deposition during operation may contribute to the diagnosis, and immunohistochemistry is very important for the diagnosis of intracranial angiosarcoma.
Supports resection with monitoring for rare meningeal angiosarcoma; leaves open need for larger studies on long-term outcomes.
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Cao et al. (2023) conducted a case report in Primary intracranial parasagittal meningeal angiosarcoma (n=1). Surgical resection, chemotherapy, and radiotherapy was evaluated on Tumor recurrence. Surgical resection followed by chemoradiotherapy resulted in no tumor recurrence and normal motor function at 9 months postoperatively in a patient with primary parasagittal meningeal angiosarcoma.
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