Measles Exposure Among Vaccine Recipients

In the interval 1961 to 1963 more than 5,000 children in our series received measles vaccines by one of three immunization schedules.1More than 90% of recipients were successfully immunized as judged by development of significant antibody in seronegative children in a random sample group (Table 1). The present report details the response upon exposure to natural measles in recipients of live virus, killed virus, and a combination of both and includes some preliminary data on persistence of antibody following administration of inactivated vaccine alone or in combination with attenuated vaccine. Method The population in the original study consisted largely of patients in the private practices of the Volunteer Faculty of the University of Colorado Medical Center and were members of families living in urban regions of Colorado and Wyoming. A smaller number of vaccinees were children of the Cadry of Lowry Air Force Base and Fitzsimons Army Hospital