What question did this study set out to answer?

To systematically review the clinical role and efficacy of therapeutic plasma exchange in managing acute complications of sickle cell disease.

June 27, 2024TransfusionOpen Access

Therapeutic plasma exchange for sickle cell disease acute complications: A systematic review

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Systematic review evaluates therapeutic plasma exchange outcomes in acute sickle cell complications, highlighting clinical utility.

To systematically review the clinical role and efficacy of therapeutic plasma exchange in managing acute complications of sickle cell disease.
Conducted a systematic review synthesizing published evidence on therapeutic plasma exchange interventions.
Evaluated clinical indications and procedural outcomes across patient cohorts experiencing acute sickle cell complications.
Identified therapeutic plasma exchange as an adjunctive intervention for severe, life-threatening acute complications of sickle cell disease.
Detailed quantitative outcomes and comparative effect sizes were unavailable in the provided abstract text.

Denoon et al. (2024) studied this question.

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