When, in 1854, Virchow recognised myelin as, if not a single substance identical with the essential constituent of the medulla of nerves, at least as a class of substances which chemically were closely allied thereto, he described it as possessing the following characteristics:— (i) When brought into contact with water it swells up, exhibiting a characteristic morphology, and developing processes of irregular and bizarre form having a double contour. (ii) Easily soluble in hot alcohol, becoming in part precipitated on cooling.
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Adami et al. (1906) studied this question.