Do Leprosy Patients Take Daps one Regularly?

Urine dapsone/creatinine (D/C) ratios were determined repeatedly in 15 hospital patients on a supervised daily dosage of dapsone. Figures for the group as a whole covered a wide range, but those for individual patients clustered within that range and were much less variable. D/C ratios were ais o determined in '89 out-patients prescribed daily dosage of dapsone. Thirty-nine patients gave figures lower than any fo und in the supervised group, and it was estimated that this group of patients had taken about 42% of their prescribed dosage in the previous 24 to 28 h.