In the Goulstonian Lectures, delivered in 1919, one of us (W. W. C. T.) discussed the possibility of attacking epidemiological problems by the method of direct experiment, and reported a few preliminary observations on the spread of enteric infection among mice. Since then a series of reports have been published dealing with the investigation of particular problems along these lines (Topley, 1921 a and b, 1922 a and b, 1923, Topley and Wilson, 1923 a and b, Topley and Ayrton, 1924 a, b and c, Topley, Ayrton and Lewis, 1924 a and b, Topley, Wilson and Lewis, 1925).
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Greenwood et al. (1925) studied this question.
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